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- W2374735378 abstract "Objective To assess the effect of blood lead level on T-lymphocyte subpopulation expression and the association of T-lymphocyte subpopulation expression with threshold limit value of blood lead among children.Methods Blood lead level was measured with graphite furnace atomic absorption spectroscopy and the expression of T-lymphocyte subpopulation was measured with immunofluorescence method.T-lymphocyte subpopulation express was compared between groups with different blood levels and correlation between blood lead level and expression of T-lymphocyte subpopulation was analyzed.A total of 120 children,(64 boys and 56 girls),aged 3-6 years with a mean age of 4.5 1.5 years,were selected from the suburbs of Taiyuan city between May 2003 and October 2003.According to their blood lead levels the enrolled children were assigned into one of the three groups:26 in Group I with a blood lead level of ≥0.48 μmol/L,40 in Group 2 with a lead level of ≥0.24 μmol/L but 0.48 μmol/L,and 54 in Group 3 with a lead level of 0.24 μmol/L.Results There were no significant differences in CD3,CD4 and CD8 cell expression,CD4/CD8 cell ratio,and B-lymphocyte positive rate between Group 2 and Group 3.However,CD3 cell expression and CD4/CD8 cell ratio were lower(P0.01),and CD8 cell expression was higher(P0.05)in Group 1 when compared with Group 2.Blood level was negatively correlated with CD3 cell expression and CD4/CD8 ratio,but positively correlated with CD8 cell expression in Group 1.Conclusion High blood lead level has adverse impact on T-lymphocyte subpopulation expression." @default.
- W2374735378 created "2016-06-24" @default.
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- W2374735378 date "2010-01-01" @default.
- W2374735378 modified "2023-09-23" @default.
- W2374735378 title "The relationship between blood lead level and T-lymphocyte subpopulation expression" @default.
- W2374735378 hasPublicationYear "2010" @default.
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