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- W2374740903 abstract "OBJECTIVES:To evaluate the efficacy of rapamycin(RPM)oral liquid plus cyclosporine(CsA)on the prevenˉtion of early acute rejection after renal allograft.METHODS:20patients undergoing primary renal allografting were randomly divided into RPM trial group and Azathioprine(Aza)control group,10cases in each group,who were respectively assigned to receive CsA and adrenocortial hormones-based immunosuppression for6months,indexes including survival rates of recipients/kidneys,incidences of acute rejection and adverse reactions between2groups were compared.RESULTS:For the17patients who had finished6-month treatment,the survival rates(recipients/kidneys)were100%.Only2episodes of acute rejection occurred in one case in Aza group.Both groups had2cases of severe adverse episodes.CONCLUSIONS:The combined therapy pf RPM plus CsA is effective in the prevention of acute renal allograft rejection,and it can maintain renal function at a good level.Nevertheless,it may increase the hepatotoxicity of CsA." @default.
- W2374740903 created "2016-06-24" @default.
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- W2374740903 date "2006-01-01" @default.
- W2374740903 modified "2023-09-26" @default.
- W2374740903 title "Rapamycin Combined with Cyclosporine in the Prevention of Acute Renal Allograft Rejection:Randomized Prospective Control Study" @default.
- W2374740903 hasPublicationYear "2006" @default.
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