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- W2374770897 abstract "[Objective] To investigate the effect of catalpol in gerbils brain i schemia-reprefusion model. [Methods] Gerbils were randomly divided into three groups: sham, ischemia and catalpol. The ischemia-reprefusion model was develope d by shortly occluding common carotid arteries. After ischemia, the change situa tion of chromatin was observed by electron microscope. Cell number of apoptosis is detected with flow cytometry. The infarction fields of brain were displayed b y TTC dye. Image analysis was used to measure the percentage of the infarction a rea. [Results] Compared with the ischemia group, the morphomogy of neurons in hippocampal CA1 was normal in the group treated with catalpol. The cell number o f apoptosis markedly decreased (P0.05). And the area of infarction was also sig nificantly reduced (P 0.05). [Conclusion] Catalpol was of the effect of neuro protection." @default.
- W2374770897 created "2016-06-24" @default.
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- W2374770897 date "2005-01-01" @default.
- W2374770897 modified "2023-09-26" @default.
- W2374770897 title "Study on protective effect of catalpol against injury of ischemia-reprefusion" @default.
- W2374770897 hasPublicationYear "2005" @default.
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