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- W2374799315 abstract "Objective To investigate the efficacy and safety of recombinant human endostatin injection combined with chemotherapy in the treatment of colorectal cancer with liver metastases.Methods 64 patients were randomly divided into two groups.Control group received with FOLFOX4 and experimental group received ecombinant human endostatin injection combined with FOLFOX4.The response rates and safety of the 2 groups were observed respectively.Results The response rate of experimental group was 50.0%,and the control group was 40.6%,P 0.05.The clinical benefit rates of control group and experimental group were 53.1% and 78.1% respectively,P 0.05.The adverse reaction of the 2 groups were both Ⅰ-Ⅱ degree myelosuppression,liver dysfunction,renal dysfunction,nausea vomiting and diarrhea,only a small number of patients have Ⅲ degree leukopenia and thrombocytopenia.Conclusion Recombinant human endostatin injection combined with chemotherapy is effective and safe in the treatment of colorectal cancer with liver metastases,it is worth of further clinical study." @default.
- W2374799315 created "2016-06-24" @default.
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- W2374799315 date "2013-01-01" @default.
- W2374799315 modified "2023-09-24" @default.
- W2374799315 title "The Clinical Study of Recombinant Human Endostatin Injection Combined with Chemo therapy in The Treatment of Colorectal Cancer with Liver Metastases" @default.
- W2374799315 hasPublicationYear "2013" @default.
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