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- W2374811711 abstract "Objective According to analgesic mechanism of the capsicin(CAP),to research its acute desensitizing(analgesic) effect on prosopalgia.Methed A 30mM solution of capsicin was prepared for subcutaneous injection at infraorbital region to infiltrate trigeminal nerve branch.The volume of solution injected at a time for each rat was 20μl(group A),30μl(group B),50μl(group C)and 100μl (group D) respectively.Using“Heat pain checker”to measure pain threshold in the different time,and to observe the changes of rat's behavior.Results The time spending to obtaining desencitization for each group was as follows:group A—72-120 hrs,B—12-24 hrs,C—8-12 hrs and D—2-4hrs.When the desencitization was derived,a maintence administration of CAP was made with an interval of 24,48,72 and 96 hrs for group A,B,C and D respectively,and it should be carry on until the total dosage was equal to 50mg/kg.It showed that there was not notable difference among the recovering rate of all groups(X 0.122 of each group).Conclusion CAP infiltration at infraorbital region in rat can produce strong analgesic effect." @default.
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- W2374811711 date "2001-01-01" @default.
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- W2374811711 title "An Experimental Study of Acute Desensitization with Capsicin to Treat the Prosopalgia" @default.
- W2374811711 hasPublicationYear "2001" @default.
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