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- W2374838247 abstract "Objective To access the developmental changes of electrocardiogram(ECG) in Kunming mice,which may offer some references for physiological and pathological-electrophysiology study.Methods Limb lead ECG were recorded with self-made silver electrodes in 309 unsedated Kunming mice(days 1,3,7,14,21,28,35,60) with electrophysiology apparutus(lead-2000).Heart rate variabilty was recorded and analyzed by cardio electrocardial work station.Results The heart rhythm was sinus rhythm and heart rate was 428.96±93.62(254-789) beats/min.Sinus RR interval gradually decreased from 138.89±3.85 ms to 116.75±5.48 ms to 109.22±5.06 ms in 1 d,7 d,14 d.The 5 groups(day 14,21,28,35 and 60) were different from group day 1.PR,QRS,QT,JT interval progressively decreased with development.Similarly,the JT interval decreased from 46.66±3.56 ms at day 1 to 40.40±3.46 ms at day 7,28.22±1.91 ms at day 14 neonatal mice,and without statistic significance at day 14,21,28,35 and 60 day(all P0.001).All 5 groups were significantly different from day 1.The J-S-T segment elevation was observed at day 1 neonatal mice,decreased at day 14,and disappeaerd at day 35.The heart rate variability(HRV) increased by day.Conclusion The heart rates increase with age development in Kunming mice.accordingly,PR,QRS,QT,JT intervals decrease and independent to heart rates.J-ST-T resultant wave is observed in day 1 neonatal mice,decreased at day 14 and disappeares in 35 day." @default.
- W2374838247 created "2016-06-24" @default.
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- W2374838247 date "2010-01-01" @default.
- W2374838247 modified "2023-09-24" @default.
- W2374838247 title "Variation of electrocardial parameters by day in Kunming mice" @default.
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