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- W2374855206 abstract "Objective:To prove that appropriate intermittent exercises at ischemia threshold intension could safely promote coronary collateral formation in ischemic area Method:A balloon obturator was surgically implanted in the first obtuse marginal coronary artery (OM1) of miniature pigs. The subjects were divided into 3 groups: sham-operated (SO), pure ischemia (PI), and exercises training (ET). Subjects in ET group performed individualized treadmill programs for 8 weeks with 2 episodes of exercises-induced ischemia; 2 pre-exercises episodes of pure ischemia induced by brief OM1 occlusion were also conducted. Only pure ischemia was induced in PI group, and SO group remained sedentary for the experimental period. Capillary density (CD) was measured by immunohistochemistry; relative myocardial blood flow (RMBF) by microspheres. Light microscope and electron microscope were also employed to examine whether there was some damage in ischemic area. Result: The CD in the ET group was statistically higher than those in PI and SO groups (P0.01, P0.01), the CD in PI group was significantly higher than that in SO group (P0.01). The results of RMBF were just the same as CD. There was no myocardial damage in ET or PI group by light microscope and electron microscope.Conclusion: Intermittent exercises at ischemia threshold intension could safely promote coronary collateral formation in a porcine model." @default.
- W2374855206 created "2016-06-24" @default.
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- W2374855206 date "2008-01-01" @default.
- W2374855206 modified "2023-09-28" @default.
- W2374855206 title "Effect of intermittent exercises on ischemia threshold intension on coronary collateral formation" @default.
- W2374855206 hasPublicationYear "2008" @default.
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