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- W2374876503 abstract "Objective To investigate the restorative effect of connective tissue growth factor(CTGF) and transforming growth factor-beta(TGF-β) on segmental bone defects of the radius in rabbits.Methods An adult rabbit radius fracture model was made and treated with CTGF and TGF-β respectively or in combination in the bone defect site.The repair capability was evaluated by histological and radiographic examinations at the 4th,8th and 12th week and by biomechanical tests at the 12th week after operation.Results Both CTGF group and TGF-β group excelled significantly control group in aspects of quantity of X-ray observation,histological and biomechanical testing at 12 weeks.The combination of them brought better results as compared to the application independently.Conclusion The restorative effect of CTGF/TGF-β compound on the early bone repair is superior to CTGF or TGF-β alone.CTGF and TGF-β has good synergy in the process of bone defect repair." @default.
- W2374876503 created "2016-06-24" @default.
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- W2374876503 date "2013-01-01" @default.
- W2374876503 modified "2023-09-26" @default.
- W2374876503 title "Restorative Effects of Connective Tissue Growth Factor and Transforming Growth Factor-Beta on Bone Defects of Radius in Rabbit" @default.
- W2374876503 hasPublicationYear "2013" @default.
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