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- W2374885693 abstract "Objective To observe the expression of OPN,COX-2 and VEGF in osteosarcoma.Methods The expression of Osteopontin,COX-2 and VEGF in 38 cases with osteosarcoma was examined with immunohistochemistry.Results The total positive rate of OPN,COX-2 and VEGF was 60.53%,63.16%,68.42%,respectively.There was significant difference among different malignant osteosarcoma(P0.05),and the expression was correlated with the malignant degree.VEGF expression was positively correlated with the expression of OPN and COX-2.Conclusion OPN,COX-2 and VEGF play a role in the pathogenesis of osteosarcoma,OPN and COX-2 are regulatory factors of VEGF expression.OPN expression may be an early molecular event in the process of tumorigenesis and could be used as a biological marker to monitor the malignant process of osteosarcoma." @default.
- W2374885693 created "2016-06-24" @default.
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- W2374885693 date "2006-01-01" @default.
- W2374885693 modified "2023-09-25" @default.
- W2374885693 title "Expression of Osteopontin,COX-2 and VEGF in Osteosarcoma" @default.
- W2374885693 hasPublicationYear "2006" @default.
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