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- W2374930238 abstract "ObjectiveTo investigate the level of type ⅡA phospholipase A2 (PLA2GⅡA) mRNA and its significance in diagnosing and prognosing colorectal carcinoma.Methods Total RNA were extracted from the tissues of far end,surrounding and central areas of colorectal carcinoma,respectively.The level of PLA2GⅡA mRNA in each sample was detected by RT-PCR.Results The level of PL2GⅡA mRNA in colorectal carcinoma tissue was significantly higher than that in the tumor-shrouding tissue and the far end of tumor tissue,and the positive rate of PLA2GⅡA in these three types of tissue were 90.91%,66.67% and 51.52% respectively (P0.05).Tumor tissue showed higher level of PLA2GⅡA mRNA in female,earlier stage and patients without metastasis than that in male,terminal stage and patients with metastasis,the difference of which was statistically significant (P0.05).Conclusions PLA2GⅡA may play an important role in the process of occurrence and development of colorectal carcinoma." @default.
- W2374930238 created "2016-06-24" @default.
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- W2374930238 date "2011-01-01" @default.
- W2374930238 modified "2023-09-25" @default.
- W2374930238 title "The level of type IIA phospholipase A_2 mRNA in colorectal carcinoma and its significance" @default.
- W2374930238 hasPublicationYear "2011" @default.
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