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- W2374931272 abstract "AIM To evalueate the protective effects of four main flavonoids in Scutellaria baicalensis Georgi on oxidative injury of rat cortex mitochondria METHODS Lipid peroxidation was induced by three different system, egascorbic acidFe 2+ , 2,2azobis (2amidinopropane) hydrochloride and NADPH; the swelling of mitochondria and the decreasing of membrane fluidity were induced by ascorbic acidFe 2+ system RESULTS Baicalein, baicalin, wogonin and wogonoside at 10 μmol·L -1 can protect mitochondria from NADPH induced lipid peroxidation, while only baicalein and baicalin showed remarkable effects on ascorbic acidFe 2+ and AAPH induced lipid peroxidation The swelling of mitochondria and the decreasing of membrane fluidity induced by ascorbic acidFe 2+ system can be retarded more or less by these four flavoids CONCLUSION Flavonoids in Scutellaria baicalensis Georgi may protect mitochondria from oxdative injury induced in different ways Baicalein is the most effective flavonoids among the tested agents in different systems" @default.
- W2374931272 created "2016-06-24" @default.
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- W2374931272 date "2000-01-01" @default.
- W2374931272 modified "2023-09-25" @default.
- W2374931272 title "Protective effects of flavonoids extracted from Scutellaria Baicalensis Georgi on free radical induced rat cortex mitochondria injury" @default.
- W2374931272 hasPublicationYear "2000" @default.
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