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- W2374942654 abstract "【Objective】 Observe effect of pravastatin in treatment of acute coronary syndrome and influence affecting CRP,MMP-1 and ILs.【Methods】 Divided 54 patients in to T group and NT group according to whether pravastatin was applied,chose 20 healthy human as control group.Total efficacy of NT group and T group was observed and compared;ELISA was applied to detect CRP,MMP-1 and ILs in serum of patients.【Results】 Total curative efficacy of T group was 95.24%,significantly higher than 83.33% of NT group(P 0.05);Compared with control,CRP,MMP-1 and IL-8,IL-6 and IL-18 in serum of ACS patients were significantly increased(P 0.05),but level of IL-10 was not changed significantly.Besides,compared with situation before treatment,CRP,MMP-1 and IL-8,IL-6 and IL-18 level in ACS patient were significantly decreased(P 0.05),especially in T group(P 0.05),except IL-10(P 0.05).【Conclusion】 Occurrence of ACS is highly related with inflammation and imbalance of inflammatory factors,applying pravastatin could effectively inhibit inflammation,presenting confirmed curative effects." @default.
- W2374942654 created "2016-06-24" @default.
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- W2374942654 date "2012-01-01" @default.
- W2374942654 modified "2023-09-25" @default.
- W2374942654 title "Clinical effects of applying pravastatin in treatment of acute coronary syndrome and its influence of inflammation" @default.
- W2374942654 hasPublicationYear "2012" @default.
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