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- W2374949140 abstract "Objective:To investigate the effects of electroacupuncture(EA) on the expression of nerve growth factor(NGF) in hippocampus of rats with cerebral ischemia reperfusion(CI/R) and the neuroprotective mechanism of anti-injury in CI/R.Methods:90 SD rats were randomly divided into sham operation group(n=30),model group(n=30) and EA group(n=30),and 3 groups were evenly divided into 24h,48h and 72h subgroups.CI/R model was established by middle cerebral artery occlusion(MCAO) and reperfusion with the suture in MCA.EA was applied toDazhui(GV 14) and bilat-eralm Neiguan(PC 6).The expression of NGF protein in hippocampus were assayed by immunohistochemistry.Results:In comparison with sham operation group,NGF expression cells of hippocampus in 24 h of model group,and every 48h and 72h subgroup of model group were significantly increase.Compared with 24h,48h and 72h subgroups of model group,NGF expression cells in the corresponding subgroups of EA group were significantly increase,and its level has reached the maximum in the 48h subgroups of EA group.Conclusion:EA can strengthen the expression of NGF in hippocampus of rats with CI/R,which may contribute to the protective effect of EA on ischemic neurons." @default.
- W2374949140 created "2016-06-24" @default.
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- W2374949140 date "2009-01-01" @default.
- W2374949140 modified "2023-09-25" @default.
- W2374949140 title "Effects of Electroacupuncture on the Expression of Nerve Growth Factor in Hippocampus of Rats with Cerebral Ischemia Reperfusion" @default.
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