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- W2374982076 abstract "Objective To analyze the characteristics of 11 cases with medullary sponge kidney(MSK) in childhood.Methods The clinical information was summarized in 11 children with MSK who were hospitalized in Tongji Hospital from January 1990 to April 2011.Results There were 9 boys and 2 girls in 11 cases aged from 3 months to 11 years,with 5 cases younger than 3 years old and 6 cases elder than 3 years old.Five cases were hospitalized for renal symptoms like urorrhagia,frequent micturition,urgent urination and odynuria.The other 6 cases were hospitalized for extrarenal symptoms like fever,vomiting,growth retardation,diarrhea and cough.Diagnosis of MSK in these children was taken based on renal ultrasonography,intravenous pyelography or computed tomography.Most patients were accompanied by other renal diseases or extrarenal diseases,such as distal renal tubular acidosis in 9 cases,renal anemia in 4 cases,renal calcification in 3 cases,Carolis's syndrome in 1 case,malnutrition and growth retardation in 5 cases,cystinuria in 2 cases,generalized aminoaciduria in 2 cases and vitamin D-resistant rickets in 2 cases.Acute renal failure was found in 1 case and chronic renal failure in 3 cases.The patients all had bilateral pathological changes according to the result of abdominal plain films,renal ultrasonography,intravenous pyelography or computed tomography.IVP showed lesions in kidneys reaching one to three centra,and bilateral lesions were symmetrical.Conclusions MSK was mainly found in adults,rarely in childhood.Childhood onset of MSK was often due to the accompany of renal diseases or extrarenal diseases,which led to prominent calcification or calculus of kidney and resulted in early occurance of symptoms or signs.Therefore,renal ultrasonography,intravenous pyelography or computed tomography should be performed in children manifesting multiple renal calculi,recurrent urinary tract infection and renal failure in order to find MSK at early stage." @default.
- W2374982076 created "2016-06-24" @default.
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- W2374982076 date "2012-01-01" @default.
- W2374982076 modified "2023-09-26" @default.
- W2374982076 title "Clinical analysis of 11 cases with medullary sponge kidney in children" @default.
- W2374982076 hasPublicationYear "2012" @default.
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