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- W2374994057 abstract "Objective To evaluate the effect of patient-controlled intraven ous analgesia(PCIA) following intracranial surgery with tramadol and lidocaine. Methods Forty-eight patients undergoing elective intracranial s urgery were randomly and evenly divided into three groups:(I)tramadol 10 mg/ml+l idocaine 10 mg/ml; (Ⅱ)tramadol 10 mg/ml; (III) control group. The duration of o peration,total dose of fentanyl within operation were recorded, heart rate(HR), mean arterial pressure(MAP) , respiratory rate(RR) and pupil size before operati on and at 6, 18 and 24 h after operation were also recorded. Visual analog s cores(VAS), Ramsay sedation scores, nausea and vomiting scores, parameter of the PCIA pump at 6, 18 and 24 h after operation were also recorded. Res u lts Group Ⅰ and Ⅱ had significantly lower VAS scores than that of gr o up Ⅲ at 6 h after operation(P0.01 and P0.05),group Ⅰ had significantly lower VAS scores than that of group Ⅱ and Ⅲ at 18 h after o peration(P0.05), but there was no significant difference in VAS sco res at 24 h after operation among three groups(P0.05). There were a l so no significant difference in Ramsay scores, nausea and vomiting scores, pupil size, MAP and RR among three groups at any time(P0.05). HR were si gnificantly higher at 6, 18 h after operation than those before operation in gro u p Ⅱ and Ⅲ (P0.05). Conclusion PCIA with trama dol associated lidocaine is a nearly ideal choice for neurosurgical patients." @default.
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- W2374994057 date "2004-01-01" @default.
- W2374994057 modified "2023-09-24" @default.
- W2374994057 title "Patient-controlled analgesia following intracranial surgery with tramadol and lidocaine" @default.
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