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- W2375024664 abstract "Objective To determine whether adjacent segment degeneration is due to disease progression or a fusion-associated phenomenon. Methods Random 251 patients underwent lumbar single segment(L2、3, L3、4, L4、5) posterior decompression discectomy, interbody fusion and internal fixation between January 2003 and January 2008. Of which, 104 patients were followed up with an average follow-up time of 59.3 months(48-86 months). The patients was divided into groups A and B. Segments adjacent to fusion levels were allocated to group A, and the others were allocated to group B. The patients were divided according to age greater than 50 years old and less than 50 years old. The risk of the degeneration was analyzed.Pfirrmann grading standard was used to assess intervertebral disc degeneration. Results One hundred and four patients were followed up, 51 segments of total 416 segments degenerated(12.3%), while 31 segments of 208 adjacent segments degenerated(14.9%) in group A and 20 segments of non-adjacent segments degenerated(9.6%) in group B. There was no statistically significant difference in segment degeneration between group A and group B. In 60 patients of more than 50 years old, 39 segments of 240 segments(16.3%) degenerated. In 44 patients of less than 50 years old, 12 segments of 176 segments(6.8%)degenerated. There was statistically significant difference in segment degeneration between patients of older than 50 years old and less than 50 years old. Conclusion The fusion possibly accelerates the severity of adjacent level degeneration, but no significant difference is observed between adjacent and non-adjacent segments. In the adjacent segment degeneration, the natural history of lumbar disease is more important than the presence of fusion." @default.
- W2375024664 created "2016-06-24" @default.
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- W2375024664 date "2014-01-01" @default.
- W2375024664 modified "2023-09-23" @default.
- W2375024664 title "Adjacent segment degenerative disease: is due to disease progression or a fusion-associated phenomenon?" @default.
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