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- W2375081868 abstract "Objective:To observe the curative effect and safety of combination chemotherapy of docetaxel(DXL)combined with cisplatin(DDP)for anthracycline(ANT)-resistant advanced breast cancer(ABC).Methods:From January 2002 to June 2006,40 patients with ANT-resistant advanced breast cancer were treated with combination chemotherapy of DXL and DDP.DXL 75 mg/m2 on d1 and DDP 30 mg/m2 was used on d1-3 every three weeks.The median number of cycles was 4(range:2-8 cycles).Results:Three patients achieved complete response(7.5%)and 19 partial response(47.5%),9 stable disease(22.5%).The overall response rate was 55%,median survival time was 6 months,One year survival rate was 66.7%,the main side effects were gastrointestinal and hematologic toxicities.Conclusion:Docetaxel and cisplatin combination is active in the treatment for anthracycline-resistant advanced breast cancer patient with an acceptable toxicity,and may be a therapeutic alternative after anthracycline regimen faild." @default.
- W2375081868 created "2016-06-24" @default.
- W2375081868 creator A5081213152 @default.
- W2375081868 date "2008-01-01" @default.
- W2375081868 modified "2023-09-25" @default.
- W2375081868 title "Docetaxel combined with cisplatin in the treatment of anthracyclines resistant advanced breast cancer" @default.
- W2375081868 hasPublicationYear "2008" @default.
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