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- W2375145797 abstract "Objective To investigate the relationship between the inflammatory degree of ulcerative colitis(UC)and the expression of adhesion molecules CD44,CD62p and CD54 in peripheral blood.Methods The expressions of adhesion molecules CD44,CD62p and CD54 in peripheral blood were determined by FCM method in 42 patients with UC including 20 cases in light degree group,8 cases in moderate degree group,6 cases in severe degree group,8 cases in remission group,30 healthy subjects were enrolled as control group.Results The levels of CD44,CD62p in moderate degree group and severe degree group were highest,next light degree group and remission group,while that in control group were lowest,there were significant differences among the five groups(P0.01).The levels of CD54 in moderate degree group and severe degree group were significantly higher than that of light degree group(P0.05),and which in moderate degree group and severe degree group were significantly higher than those in remission group and control group(P0.01).The positive expression of CD54 in remission group was significantly higher than that of control group(P0.01).Conclusion CD44,CD62p and CD54 play important roles in the pathogenesis of UC,and its levels can reflex the severe degree of illness,which is helpful to guide clinical treatment for UC." @default.
- W2375145797 created "2016-06-24" @default.
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- W2375145797 date "2008-01-01" @default.
- W2375145797 modified "2023-09-24" @default.
- W2375145797 title "The relationship between inflammatory degree of ulcerative colitis and the expression of CD44,CD62p and CD54" @default.
- W2375145797 hasPublicationYear "2008" @default.
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