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- W2375152060 abstract "Objective To investigate the effects of ischemia-reperfusion injury on nerve regeneration of the organotypic brain slices from neonatal SD rats.Methods Brain slices(300 μm)from postnatal 3rd day(P3)SD rats were prepared and randomly divided into two groups:ischemia-reperfusion group and control group.Each group was cultured in the same condition and received the same treatment.After that,changes were observed under invert microscope or detected by immunofluorescence staining.Resultss Nestin-positive neonatal cells were found in the subventrical zone and hippocampal dentate gyrus after brain slices endured ischemia-reperfusion injury,while there were no neonatal cells in the same area of control group.The number of neonatal cells increased greatly after brain slices of both groups received treatment,and the brain slices of control group had more neonatal cells(P0.01).The density of neonatal cells in the subventrical zone and hippocampal dentate gyrus decreased due to cell migration as time went on.Conclusion Ischemia-reperfusion injury could induce nerve regeneration of the organotypic brain slices from neonatal SD rats,but it also could damage long-term nerve regeneration at the same time." @default.
- W2375152060 created "2016-06-24" @default.
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- W2375152060 date "2008-01-01" @default.
- W2375152060 modified "2023-09-27" @default.
- W2375152060 title "Effects of ischemia-reperfusion injury on nerve regeneration of the organotypic brain slices from neonatal SD rats" @default.
- W2375152060 hasPublicationYear "2008" @default.
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