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- W2375152315 abstract "Objective To research the effect of CAP on CGRP and NOS immunoreactive nerve in rat facial skin, and to explore the analgesic mechanism of CAP in treating prosopalgia thereby. Methods A 30mM-solution of capsicin was prepared for subcutaneous injection at infraorbital region to infiltrate trigeminal nerve-branch. The volume of solution injected at a time for each rat was 20μl (group A), 30μl (group B), 50μl (group C) and 100μl (group D) respectively. 24h after injection, the tissues of relavent region were sampled for immunohistochemical obsevation and computer image analysis. Results The variance analysis showed there were very obvious and dose- dependent differences between the varient CAP-grous in comparison with the control group (P0.05), but with an exception of group A, the difference between which and control group was less-obvious (P0.01). Couclusion there is obvious influence of CAP on CGRP and NOS immunoreactive nerves in rat facial skin. The CGRP and NOS may participate in mechanisms of pain and analgesia at oro-facial region of rat." @default.
- W2375152315 created "2016-06-24" @default.
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- W2375152315 date "2004-01-01" @default.
- W2375152315 modified "2023-09-25" @default.
- W2375152315 title "Effect of CAP on the Calcitonin Gene-related Peptide ( CGRP) and Nitric Oxide Synthase (NOS)Immunoreative Nerve in Facial Skin of Rat" @default.
- W2375152315 hasPublicationYear "2004" @default.
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