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- W2375178241 abstract "In order to explore the degree of protein oxidative damage induced by gaseous formaldehyde in mice and its molecular reaction mechanism, the mice were treated with gaseous formaldehyde of different concentrations (0mg·m -3, 0.68mg.m -3 and 3?mg·m -3) for 72hours and the protein carbonyl content was measured by using spectrophotometric DNPH assay to reflect the degree of protein oxidative damage. The results showed that the protein carbonyl content in brain, heart and liver tissue of mice decreased in the group of 0.68?mg·m -3 (P0.01, P0.01, P0.05), while it increased significantly in heart and liver tissue in the group of 3.0?mg·m -3 (P0.01, P0.01), but the protein carbonyl content in brain did not have notable difference compared with the control (P0.05). These results indicated that the protein oxidative damage induced by gaseous formaldehyde depended on the concentration of gaseous formaldehyde. Low concentration formaldehyde might not induce protein oxidative damage, while medium concentration formaldehyde could cause protein oxidative damage in heart and liver tissue markedly, but it had little effect on protein of brain." @default.
- W2375178241 created "2016-06-24" @default.
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- W2375178241 date "2005-01-01" @default.
- W2375178241 modified "2023-09-28" @default.
- W2375178241 title "Study on protein oxidative damage in mice induced by gaseous formaldehyde" @default.
- W2375178241 hasPublicationYear "2005" @default.
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