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- W2375184857 abstract "OBJECTIVE To observe the effect of aspirin on diabetic cataract of rats.METHODS Rats were randomly divided into four groups:A(normal group),B(model group),C(low dosage of aspirin group),D(high dosage of aspirin group).Diabetic rats of B,C,D group were introduced by streptozotocin.The rats of C and D group were given low dosage and high dosage of asipirin by tube respectively;the rats of A and B group were given the same volume of normal saline.The changes of lens in different period were observed.Maldondialdehyde(MDA),superoxide dismutase(SOD),glutahione peroxides(GSH-px) in lens and serum was tested using fullautomatic biochemistry detector.RESULTS Compared with group B,the progress of cataract was significantly delayed in group C and D;the quantities of MDA in lens and serum decreased significantly(P0.05 or P0.01),the activity of SOD and GSH-px in lens and serum increased significantly(P0.05 or P0.01).CONCLUSION The oxidative damage may play an important role in diabetic cataracts.Aspirin could effectively inhibit diabetic cataract genesis partly through reducing oxidative damage of lens." @default.
- W2375184857 created "2016-06-24" @default.
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- W2375184857 date "2009-01-01" @default.
- W2375184857 modified "2023-09-25" @default.
- W2375184857 title "Effect of aspirin on diabetic cataract of rats" @default.
- W2375184857 hasPublicationYear "2009" @default.
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