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- W2375220453 abstract "Objective To observe the changes of matrix metalloproteinase(MMP-3)of synovial fluid in acute gouty arthritis model and the impacts on MMP-3 by the formulas for removing liver fire and stagnation,tonifying the spleen and kidney,clearing away heat and resolving damp.Methods 60 animals were randomized into normal group,model group,removing liver fire and stagnation group,the group of tonifying the spleen and kidney,clearing away heat and resolving damp,colchicine group and aceclofenac group,10 rats in each group.Corresponding drug was administered in each group.After medication,ELISA enzyme-linked immunosorbent assay was used to determine MMP-3 concentration in right ankle joints of rats.Results Compared with normal group,MMP-3 value increased apparently in model group(P0.05)and reduced in all of other groups(P0.05).Conclusion The formulas for removing liver fire and stagnation,tonifying the spleen and kidney,clearing away heat and resolving damp reduce effectively MMP-3 level in ankle joint fluid of acute gouty arthritis rat models and plays a good prevention and treatment of acute gouty arthritis." @default.
- W2375220453 created "2016-06-24" @default.
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- W2375220453 date "2009-01-01" @default.
- W2375220453 modified "2023-09-25" @default.
- W2375220453 title "Impacts of Different Compatibilities of Chinese Medicine on MMP-3 in Acute Gouty Arthritis Model" @default.
- W2375220453 hasPublicationYear "2009" @default.
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