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- W2375282425 abstract "Objective:To investigate the correlation between moesin antibody and acute coronary syndrome (ACS) and explore the relationship between moesin antibody and the severity of coronary artery lesion. Method:A total of 150 patients with ACS was divided into unstable angina (UA) group and acute myocardial infarction (AMI) group. Then all the patients were divides into three groups according to severity of coronary artery disease: single vessel group, double vessel group, three vessel and left main vessel group. Each patient was calculated the coronary artery stenosis score. Other 51 patients excluded coronary heart disease (CHD) through coronary angiography were selected into control group. Serum moesin antibody of all the patients were decteded by enzyme-linked immunosorbent assay (ELISA), the moesin antibody positive expression rates and OD values in different groups were observed. The correlation between the coronary artery stenosis scores and the OD value of moesin antibody was analysed. Result:①The positive expression rate and OD value of moesin antibody in ACS group were significantly higher than those in control group (P0.01). ②The positive expression rate and OD value in UA group were significantly higher than those in AMI group (P0.05). ③In pace with the severe of coronary artery lesions, the positive expression rate and OD value of moesin antibody were gradually increased, and there was significant difference between three-vessel and left main vessel group and single-vessel group (P0.05). ④Correlation analysis showed that there was significantly positive correlation between the OD value of moesin antibody and the coronary artery stenosis scores (r=0.601, P0.01). Conclusion:Moesin antibody may be a new marker for chronic and sustained vascular endothelial injury, which could contribute to judge the clinical type of ACS and the severity of coronary artery lesions." @default.
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- W2375282425 date "2013-01-01" @default.
- W2375282425 modified "2023-09-23" @default.
- W2375282425 title "Relevance between moesin antibody and acute coronary syndrome" @default.
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