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- W2375291465 abstract "Objective To evaluate the short term efficacy of rh-endostatin(YH-16)combined with vinorelbine(NVB regimen)in the treatment of advanced non-small cell lung cancer.Methods 60 recurrently advanced NSCLC patients were enrolled.32 patients were treated by vinorelbine plus endostar(treatment group).And 28 patients were treated by docetaxel(control group).Efficacy were estimated by imaging every two cycles.ResultsThe total effective rate(CR+PR)was 37.5%(12/32),and clinically beneficial rate(CR+PR+SD)Was 75.0%(24/32)in the treatment group,And the total effective rate(CR+PR)Was 14.3%(4/28),and clinically beneficial rate(CR+PR+SD)Was 42.9%(12/28)in the control group.There were significant differences between the two groups in effect,total effective rate and clinically beneficial rate(P0.05).There was no significant difference between the two groups in untoward effects including leucopenia and thrombocytopenia(P0.05).Conclusions The rh-endostatin combined with vinorelbine as a second-line regimen is more effective than doeetaxel monotherapy for NSCLC.It can evidently raise the effective rate and clinically beneficial rate in patients with NSCLC.and with a good safety." @default.
- W2375291465 created "2016-06-24" @default.
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- W2375291465 date "2012-01-01" @default.
- W2375291465 modified "2023-09-28" @default.
- W2375291465 title "Short term efficacy and safety of rh-endostatin combined with vinorelbine for advanced non-small cell lung cancer" @default.
- W2375291465 hasPublicationYear "2012" @default.
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