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- W2375322234 abstract "[Objective]To investigate the effect of neoadjuvant chemptherapy (NACT) in early carcinoma of cervix.[Methods]Thirty three patients with stage Ⅰa to stage Ⅱa cervical carcinoma received NACT for 2 periods of treatment before operation. The evaluation was made according to UICC on 14 days after NACT. Then the hysterectomy was done.[Results]The total efficient rate of NACT was 87%, CR 57%, PR 30%, SD 9.0%, PD 3.0%.The efficient rates of NACT of stage Ⅰ_ b1,Ⅰ_ b2, Ⅱ_a squamous carcinoma, adenocarcinoma, patients with node of tumor and 4 cm were 100%, 90.0%,71.4%,86.7%,100%,92.3% and 85.0% respectively. By evaluating the state of illness after operation, the efficient rates of stage Ⅰ_ b1,Ⅰ_ b2, Ⅱ_a, Ⅱ_b, patients with lymph node metastasis, patients with node of tumor and 4 cm were 33.3%, 60.0%, 42.8%, 5.0%, 14.2%, 7.6% and 15.0%, respectively. No vesical fistula was found after operation. The recurrence rate was 6.0% (only 2 cases developed recurrence 3 years after operation).[Conclusion]As a kind of therapy used in early cervical carcinoma before operation, NACT can shrink significantly the cervical tumor, reduce invasion and metastasis, decrease complications and the pelvic recurrence after operation." @default.
- W2375322234 created "2016-06-24" @default.
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- W2375322234 date "2006-01-01" @default.
- W2375322234 modified "2023-09-25" @default.
- W2375322234 title "Evaluation of Clinical Efficiency of Neoadjuvant Chemotherapy in Early Cervical Carcinoma" @default.
- W2375322234 hasPublicationYear "2006" @default.
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