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- W2375331878 abstract "Amphiphilic copolymer, monomethoxy-poly(ethylene glycol)-b-poly-dl-lactide (PELA), was used to prepare macroporous microspheres without adding any emulsifier or porogen, and the necessary preparation conditions for formation of macroporous microspheres and their effects on pore diameter were studied. The results indicated that stable emulsions and macroporous structure were prepared by PELA, but hydrophobic poly(lactic acid) and poly(lactide-co-glycolide) could only produce microcapsules. It was found that macroporous microspheres with the pore diameters more than 100 nm could be produced while the volume ratio of inner water phase to the volume of oil phase was between 1:4～1:2, and the microspheres were solidified through two steps. The results showed that the pore diameters of macroporous microspheres decreased as the primary emulsification rate increased. In addition a possible mechanism of the formation of macroporous microspheres was proposed." @default.
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- W2375331878 date "2007-01-01" @default.
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- W2375331878 title "Preparation of Macroporous Polymer Microspheres by Double-emulsion Method" @default.
- W2375331878 hasPublicationYear "2007" @default.
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