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- W2375336039 abstract "MicroRNA (miRNA) are a class of non-coding RNA that play an important role in gene expression and controlling. Recently,the role of miRNA in the development process of the disease has aroused general interest. Some of these miRNA bind to special target mRNA,regulating cell proliferation and differentiation of osteoblast,osteoclast and chondroeyte. and then exert an influence on bone metabolism,and lead to the occurrence of metabolic bone disease. Suggesting that there are certain relations between miRNA and metabolic bone disease. Additionally the alteration of the expression levels of some miRNA may be curative for metabolic bone disease. This review summarizes the biological activity of the miRNA and its specific role in metabolic bone diseases (osteoporosis and osteoarthritis) that miRNA play an important role in the pathogenesis of metabolic bone disease,and may have diagnostic and therapeutic potential. Furthermore,and might provide a new way of treating metabolic bone disease." @default.
- W2375336039 created "2016-06-24" @default.
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- W2375336039 date "2013-01-01" @default.
- W2375336039 modified "2023-09-26" @default.
- W2375336039 title "Progress of microRNA in metabolic bone sisease" @default.
- W2375336039 hasPublicationYear "2013" @default.
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