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- W2375355319 abstract "Objective:To investigate effects of Radix astragali (RA) on relieving insulin resistance(IR) in adipose tissue of high fat fed(HF) rats. Methods: Twenty four SD rats were divided into 3 groups randomly( n =8):HF group, HF+RA group,and normal control group. Each group was fed equicalorically for 7 weeks, then insulin sensitivity was measured by glucose insulin tolerance test. The adipose tissues in subcutanea and retroperitoneal were weighted respectively. Sections of adipose tissue were fixed with 100% ethanol and stained by TUNEL technique with a kit to detect apoptotic nuclei. Results: (1)K values obtained from glucose insulin tolerance test were significantly increased in HF+RA group compared with that in HF group. (2) The fats in the retroperitoneal position were significantly increased in HF group compared with that in HF+RA group. (3) The number of TUNEL positive nuclei in retroperitoneal adipose tissue was much greater in HF+RA group than in HF group. Conclusion: RA can relieve insulin resistance of the high fat fed rat, which may be closely related to increment of adipocyte apoptosis and reduction of intro abdominal fat weight." @default.
- W2375355319 created "2016-06-24" @default.
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- W2375355319 date "2004-01-01" @default.
- W2375355319 modified "2023-09-25" @default.
- W2375355319 title "Effect of Radix astragali on insulin sensitivity in high-fat-fed rats" @default.
- W2375355319 hasPublicationYear "2004" @default.
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