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- W2375374927 abstract "Objective:To study the antinociceptive activity and to analyze the main component of the crude aqueous solubility decoction obtained from the pericarp of castor bean (Ricinus communis ).Methods:The antinociceptive activity of the decoction were assessed by the standard rodent hyperalgesia models on the mice of chemical ( acetic acid) and thermal ( hot plate).The main components were analyzed by HPLC-MS technique.Results:Compared with the control group,this decoction produced a significant inhibition of acetic acid-induced abdominal writhing in mice and increase in latency during the observation time in the hot-plate test in a dose-dependent manner in mice(P0.001).The main components analyzed by HPLC/MS include ricinine.Conclusion:These results suggest that the crude aqueous solubility decoction of castor bean (Ricinus communis) pericarp can antagonize the acute pain caused by acetic acid and hot plate and these data show this analgesic seems to be related to interaction with the ricinine." @default.
- W2375374927 created "2016-06-24" @default.
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- W2375374927 date "2007-01-01" @default.
- W2375374927 modified "2023-09-23" @default.
- W2375374927 title "Antinociceptive activity of crude aqueous solubility decoction obtained from the pericarp of castor bean (Ricinus communis) and analysis of main components" @default.
- W2375374927 hasPublicationYear "2007" @default.
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