Matches in SemOpenAlex for { <https://semopenalex.org/work/W2375403896> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2375403896 abstract "Objective To investigate the pathobiological effect of β 2 microglobulin modified with advanced glycation end products (AGE β 2m) on human type B synovial cells.Methods The normal human type B synovial cells (HSCs) were isolated and cultured in vitro with AGE β 2m. The levels of TNF α and IL 1β in the supernatants were measured by enzyme linked immunosorbent assay (ELISA).Results AGE β 2m,but not unmodified β 2m,stimulated HSCs to produce TNF α and IL 1β with a time and dose dependent manner.These effects were inhibited by preincubation of synovial cells with an antibody against AGE receptor (RAGE).Conclusion AGE β 2m stimulates HSCs to produce TNF α and IL 1β by a pathway mediated by RAGE.These pathobiological effects of AGE β 2m might contribute to the local inflammatory response and tissue damage seen in dialysis related amyloidosis." @default.
- W2375403896 created "2016-06-24" @default.
- W2375403896 creator A5009289697 @default.
- W2375403896 date "2001-01-01" @default.
- W2375403896 modified "2023-09-24" @default.
- W2375403896 title "β_2-microglobulin modified with advanced glycation end products induces production of proinflammatory cytokines in human type B synovial cells" @default.
- W2375403896 hasPublicationYear "2001" @default.
- W2375403896 type Work @default.
- W2375403896 sameAs 2375403896 @default.
- W2375403896 citedByCount "0" @default.
- W2375403896 crossrefType "journal-article" @default.
- W2375403896 hasAuthorship W2375403896A5009289697 @default.
- W2375403896 hasConcept C147990577 @default.
- W2375403896 hasConcept C153911025 @default.
- W2375403896 hasConcept C164027704 @default.
- W2375403896 hasConcept C169760540 @default.
- W2375403896 hasConcept C170493617 @default.
- W2375403896 hasConcept C17991360 @default.
- W2375403896 hasConcept C185592680 @default.
- W2375403896 hasConcept C202751555 @default.
- W2375403896 hasConcept C203014093 @default.
- W2375403896 hasConcept C21957315 @default.
- W2375403896 hasConcept C2776914184 @default.
- W2375403896 hasConcept C2777575956 @default.
- W2375403896 hasConcept C2778857457 @default.
- W2375403896 hasConcept C55493867 @default.
- W2375403896 hasConcept C71924100 @default.
- W2375403896 hasConcept C86803240 @default.
- W2375403896 hasConceptScore W2375403896C147990577 @default.
- W2375403896 hasConceptScore W2375403896C153911025 @default.
- W2375403896 hasConceptScore W2375403896C164027704 @default.
- W2375403896 hasConceptScore W2375403896C169760540 @default.
- W2375403896 hasConceptScore W2375403896C170493617 @default.
- W2375403896 hasConceptScore W2375403896C17991360 @default.
- W2375403896 hasConceptScore W2375403896C185592680 @default.
- W2375403896 hasConceptScore W2375403896C202751555 @default.
- W2375403896 hasConceptScore W2375403896C203014093 @default.
- W2375403896 hasConceptScore W2375403896C21957315 @default.
- W2375403896 hasConceptScore W2375403896C2776914184 @default.
- W2375403896 hasConceptScore W2375403896C2777575956 @default.
- W2375403896 hasConceptScore W2375403896C2778857457 @default.
- W2375403896 hasConceptScore W2375403896C55493867 @default.
- W2375403896 hasConceptScore W2375403896C71924100 @default.
- W2375403896 hasConceptScore W2375403896C86803240 @default.
- W2375403896 hasLocation W23754038961 @default.
- W2375403896 hasOpenAccess W2375403896 @default.
- W2375403896 hasPrimaryLocation W23754038961 @default.
- W2375403896 hasRelatedWork W1605085939 @default.
- W2375403896 hasRelatedWork W177520220 @default.
- W2375403896 hasRelatedWork W188484924 @default.
- W2375403896 hasRelatedWork W1966855094 @default.
- W2375403896 hasRelatedWork W2006901157 @default.
- W2375403896 hasRelatedWork W2010140068 @default.
- W2375403896 hasRelatedWork W2013482155 @default.
- W2375403896 hasRelatedWork W2022155153 @default.
- W2375403896 hasRelatedWork W2028527478 @default.
- W2375403896 hasRelatedWork W2037699401 @default.
- W2375403896 hasRelatedWork W2041524207 @default.
- W2375403896 hasRelatedWork W2046284872 @default.
- W2375403896 hasRelatedWork W2072587667 @default.
- W2375403896 hasRelatedWork W2164592060 @default.
- W2375403896 hasRelatedWork W2365902982 @default.
- W2375403896 hasRelatedWork W2374657473 @default.
- W2375403896 hasRelatedWork W2404248979 @default.
- W2375403896 hasRelatedWork W2404959419 @default.
- W2375403896 hasRelatedWork W2469639846 @default.
- W2375403896 hasRelatedWork W2600711389 @default.
- W2375403896 isParatext "false" @default.
- W2375403896 isRetracted "false" @default.
- W2375403896 magId "2375403896" @default.
- W2375403896 workType "article" @default.