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- W2375516975 abstract "Objective: To observe the correlation between the intestinal permeability with I-FABP in plasma after gut barrier injury in rats with intraperitoneal infection.Methods: Forty healthy adult Wistar rats were randomly divided into control group(celiotomy ones only) and groups of 12,24,36,48 hours post-operation of abdominal infection respectively(These groups were treated by cecal ligation and puncture to establish abdominal infection models).Each group contained 8 rats.After the rats were anaesthetized,D-lactate and I-FABP in plasma were measured at 4 consecutive time points.Results: Intestinal barrier began to change significantly 12 h after the in-fection,The lever of D-lactate in plasma(P0.05) is higher than the control group,and reached the peak at 24h postoperation(P0.01).Meanwhile the level of I-FABP in plasma(P0.01) was higher than that of the control group,and reached the peak at 36 h postoperation(P0.01).D-lactate level also had a significant correlation with I-FABP level(r=0.626,P0.01).Conclusion: Intestinal mucosal barrier was subjected serious damage and there was a significant correlation between intestinal permeability and I-FABP level in plasma in rats with intraperitoneal infection." @default.
- W2375516975 created "2016-06-24" @default.
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- W2375516975 date "2013-01-01" @default.
- W2375516975 modified "2023-09-25" @default.
- W2375516975 title "Study on Correlation between Intestinal Permeability and I-fabp in Plasma in Rats with Intraperitoneal Infection" @default.
- W2375516975 hasPublicationYear "2013" @default.
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