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- W2375518961 abstract "Objective:To study the human telomerase reverse transcriptase(hTERT) activity and expression of PTEN protein in squama cell carcinoma of tongue and to investigate their relations during histogenesis and development of squama cell carcinoma of tongue.Method:Totally 50 cases of squama cell carcinoma of tongue tissues were studied.The hTERT activity was detected using hTERT ISH detection Kit.PTEN protein in squama cell carcinoma of tongue was detected by immunohistochemical LASB method.Result:The positive staining rates of hTERT and PTEN protein in squama cell carcinoma of tongue were 74.5%(37/50)and 39.1%(20/50) respectively.Expression of hTERT was positively correlated with the malignant degsee of squama cell carcinoma of tongue(P0.01).hTERT activity was associated with PTEN expression in squama cell carcinoma of tongue(P0.01).Conclusion:hTERT activity correlates with the degree of the neoplastic differentiation,and may be an important marker for the malignancy of squama cell carcinoma of tongue.PTEN may affect hTERT activity." @default.
- W2375518961 created "2016-06-24" @default.
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- W2375518961 date "2006-01-01" @default.
- W2375518961 modified "2023-09-27" @default.
- W2375518961 title "Relationship between hTERT and PTEN expression in squama cell carcinoma of tongue" @default.
- W2375518961 hasPublicationYear "2006" @default.
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