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- W2375568314 abstract "OBJECTIVE To observe the effects of Astragalus combined with prepared Rehmannia root on bone mineral content and biomechanics of ovariectomized rats.METHODS Sixty ovariectomized rats were randomly divided into six groups: Astragalus group(A),prepared Rehmannia root group(R),the Astragalus combined with prepared Rehmannia root group(A+R),ethinylestradiol group(E),ovariectomized group(OVX) and sham-operated(SHAM).Rats were given the corresponding drugs through intragastric adiministration.16 weeks later,rats were killed and bone slices were made.Measured bone mineral content,blood index and biomechanics changes of the 2nd lumbar vertebra.RESULTS In comparison with OVX,E and A+R group could obviously increase E2 and maximum load(P0.01) and reduce BGP markedly(P0.01).A+R group could also obviously reduce ALP in blood(P0.05).The bone mineral content,maximum stress and modulus of elasticity of A+R and R group were markedly increased(P0.05).CONCLUSION Astragalus combined with prepared Rehmannia root could increase the bone mineral content,change the correlative blood indexes and bone biomechanics indexes,reduce bone turnover,so it can slow down the osteoporosis formation of ovariectomized rats." @default.
- W2375568314 created "2016-06-24" @default.
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- W2375568314 date "2013-01-01" @default.
- W2375568314 modified "2023-09-26" @default.
- W2375568314 title "Effects of Astragalus combined with prepared Rehmannia root on bone mineral content and biomechanics of ovariectomized rats" @default.
- W2375568314 hasPublicationYear "2013" @default.
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