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- W2375666988 abstract "Objective The study investigated the psychosocial risk factors in treatment resistant depression patients.Methods 30 treatment resistant depression patients,30 treatment non-resistant depression patients and 30 normal controls were involve in the study.All the subjects themselves completed the following questionnaires:general condition questionnaire,EPQ,LES,SSRS,HAMD and HAMA were evaluated by the researcher.Utilizing t test,χ2 test,Pearson correlation,analysis of variance and stepwise regression analysis were used to statistic the collected data in SPSS10.0.Results There were lower score of Extraversion and higher score of Neuroticism in TRD patients than TNRD patients and the normal group.The TRD patients showed significantly increased scores in negative life events and social intercourse problems,decreased total scores in social support and objective support.The total score of HAMD was positively related to the scores of negative life events,pschoticism and neuroticism of EPQ,negatively related to scores of social support,subjective support,objective support and utilization of social support.The total score of HAMA was positively related to the scores of negative life events and Neuroticism of EPQ,negatively related to scores of Extraversion of EPQ,social support and utilization of social support.The factors which entered regression equation were as follows:The negative life events and lower social support were the risk factors leading to depression.So was Neuroticism of EPQ leading to anxiety.Conclusions Introversion,Neuroticism,experienced more negative life events,lower social support are the main risk factors of TRD.Stress and social support have actions on the severity and prognosis in TRD." @default.
- W2375666988 created "2016-06-24" @default.
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- W2375666988 date "2011-01-01" @default.
- W2375666988 modified "2023-09-26" @default.
- W2375666988 title "A correlative study of the psychosocial factors in treatment resistant depression patients." @default.
- W2375666988 hasPublicationYear "2011" @default.
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