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- W2375690798 abstract "Objective To observe multioncogenes expression and investigate their relations with pathobiological characteristic in breast cancer.MethodsThe SP immunohistochemical staining method were adopted to examine the expressions of multioncogenes(ER,PR,C-erbB-2,p53,nm23,Bcl-2,PCNA,MRP) in 120 samples of breast cancer tissues.ResultsThe expressions of p53,Bcl-2 were correlatd with ER,PR state: the expression of p53 was significantly higher in ER,PR negative expressions than that in ER,PR positive expressions,P0.01;the expression of Bcl-2 was significantly lower in ER,PR negative expressions than that in ER,PR positive expressions,P0.005.Moreover,the expression of Bcl-2 in premenopause was significantly higher than that in postmenopause,P0.01.The expression of PCNA was correlatd with tumor size:it was significantly higher in patients with tumor size 3 cm than that in patients with tumor size ≤3 cm.ConclusionsThe expressions of p53,Bcl-2 were significantly correlatd with ER,PR state and may be used as important index to estimate the biological behaviour and prognosis of breast cancer." @default.
- W2375690798 created "2016-06-24" @default.
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- W2375690798 date "2008-01-01" @default.
- W2375690798 modified "2023-09-23" @default.
- W2375690798 title "Relationships between multioncogenes expression and pathobiological characteristic in Breast Cancer" @default.
- W2375690798 hasPublicationYear "2008" @default.
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