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- W2375697741 abstract "Objective:To elucidate the relationship of MSI and LOH in cervical carcinoma.Melhods:adjacent noncancerous tissues and peripheral vein blood as well as clinical stages and pathological grades were detected using p53(D17S786) and 9p21 (D9S171) as two microsatellite merkers and PCRbased silver staining technology.Results:The microsatellite polymorphism analysis in 48 cases of cervical carcinoma tissues showed that the positive MSI and LOH are 56% and 25% respectively.Clinically pathological grades showed significant difference in statistical analysis.Conclusions:The tumer suppressor gene inactivation on the two different Loci p53 (D17s786) and 9p21 (D9S171) on chromosomes 17 and 19 and MSI may be important factors in the genesis and development of cervical carcinoma." @default.
- W2375697741 created "2016-06-24" @default.
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- W2375697741 date "2000-01-01" @default.
- W2375697741 modified "2023-09-26" @default.
- W2375697741 title "The Relationship of MSI and LOH to Cervical Carcinoma and its Clinically Biological Significance" @default.
- W2375697741 hasPublicationYear "2000" @default.
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