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- W2375702957 abstract "Objective:To explore the relationship between serum IL-8, TNF-αand cervical UU/CT infection and threatened abortion.Methods:①80 patients selected were divided into threatened abortion group (TA group, n =47) and normal early pregnancy group (NEP group, n =33), and drew-out venous blood to determine serum IL-8 and TNF-α.②Chlamydia trachomatis (CT), ureaplasma urealyticun (UU) DNA in cervical secretions collected in two groups were determined by polymerase chain reaction (PCR). ③The patients with threatened abortion with positive UU/CT were given antibiotic (erythromycin). Then serum IL-8 and TNF-αbefore and after treatment were compared. ④The patients successfully cured by erythromycin were followed up till delivery.Results:①There was significant difference in UU/CT infection rate of cervical secretion between TA group (76.60%) and NEP group (21.21%) ( P 0.01). ②There was significant difference in serum IL-8, TNF-αlevel in TA group before and after treatment ( P 0.01).③Abnormality was not found in any newborn delivered by patients with threatened abortion successfully cured by erythromycin.Conclusion:①Threatened abortion is closely related to infection. ②IL-8 and TNF-αcould be used as monitor index of threatened abortion." @default.
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- W2375702957 date "2005-01-01" @default.
- W2375702957 modified "2023-09-25" @default.
- W2375702957 title "The relationship between serum IL-8, TNF-α and cervical UU/CT infection and threatened abortion" @default.
- W2375702957 hasPublicationYear "2005" @default.
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