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- W2375752521 abstract "Objective To evaluate the effect of Reduced Glutathione(GSH) in improving myocardium reperfusion in patients with acute myocardial infarction(AMI) after the emergency percutaneous coronary intervention(PCI) by 99mTc-tetrofosmin(P53) myocardium reperfusion temography (SPECT).Methods Fifty-eight patients with a first AMI shortly after PCI were randomly divided into the GSH group(n=30) and the control group(n=28).In GSH group,patients were treated routinely (Low weight heparin,Aspirin,Boliwei,Nitroglcerine and so on) plus GSH and the control group with routine treatment only.The SPECT was performed simultaneously and 15 days after PCI on all patients.Results (1)No significant difference of baseline clinical characteristics was found between the two groups before or shortly after PCI.(2)The ischemic myocardial area of the GSH group were significantly lower than that in the control group fifteen days after PCI.(3)Compared with the control group,the LVEF (left ventricular ejection fraction),LVEDV(left ventricular end-diastolic volume) and LVESV(left ventricular end-systolic volume) of the GSH group were more improved fifteen days after PCI.Conclusion Introvenous administration of GSH shortly after PCI can improve myocardial reperfusion,leading to better functional outcome than with PCI alone." @default.
- W2375752521 created "2016-06-24" @default.
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- W2375752521 date "2005-01-01" @default.
- W2375752521 modified "2023-09-23" @default.
- W2375752521 title "The Observation of Effects of Reduced Glutathione(GSH) in Improving Myocardium Reperfusion in Acute Myocardial Infarction" @default.
- W2375752521 hasPublicationYear "2005" @default.
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