FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2375757795> ?p ?o ?g. }

• W2375757795 endingPage "161" @default.
• W2375757795 startingPage "151" @default.
• W2375757795 abstract "Hypothyroidism during early development leads to numerous morphological, biochemical and functional changes in developing brain. In this study, we investigated the effects of voluntary and treadmill exercise on learning, memory and hippocampal BDNF levels in both hypothyroid male and female rat pups. To induce hypothyroidism in the mothers, 6-propyl-2-thiouracil (PTU) was added to their drinking water (100 mg/L) from their embryonic day 6 to their postnatal day (PND) 21. For 14 days, from PNDs 31 to 44, the rat pups were trained with one of the two different exercise protocols, namely the mild treadmill exercise and the voluntary wheel exercise. On PNDs 45–52, a water maze was used for testing their learning and memory ability. The rats were sacrificed one day later and their BDNF levels were then measured in the hippocampus. The findings of the present study indicate that hypothyroidism during the fetal period and the early postnatal period is associated with the impairment of spatial learning and memory and reduced hippocampal BDNF levels in both male and female rat offspring. Both the short-term treadmill exercise and the voluntary wheel exercise performed during the postnatal period reverse the behavioral and neurochemical deficits induced by developmental thyroid hormone insufficiency in both male and female rat offspring. The findings of this study thus demonstrate a marked reversibility of both behavioral and neurochemical disorders induced by developmental thyroid hormone insufficiency through the performance of exercise." @default.
• W2375757795 created "2016-06-24" @default.
• W2375757795 creator A5056164561 @default.
• W2375757795 creator A5057333741 @default.
• W2375757795 creator A5081658503 @default.
• W2375757795 date "2016-08-01" @default.
• W2375757795 modified "2023-09-23" @default.
• W2375757795 title "Effects of maternal hypothyroidism during pregnancy on learning, memory and hippocampal BDNF in rat pups: Beneficial effects of exercise" @default.
• W2375757795 cites W1919133853 @default.
• W2375757795 cites W1921453882 @default.
• W2375757795 cites W1968761011 @default.
• W2375757795 cites W1970516662 @default.
• W2375757795 cites W1976537318 @default.
• W2375757795 cites W1977160866 @default.
• W2375757795 cites W1979030149 @default.
• W2375757795 cites W1985138331 @default.
• W2375757795 cites W1986796288 @default.
• W2375757795 cites W1988549686 @default.
• W2375757795 cites W1989795214 @default.
• W2375757795 cites W1990050324 @default.
• W2375757795 cites W1994845177 @default.
• W2375757795 cites W1997376959 @default.
• W2375757795 cites W2002197081 @default.
• W2375757795 cites W2002199406 @default.
• W2375757795 cites W2002363989 @default.
• W2375757795 cites W2004840471 @default.
• W2375757795 cites W2007734870 @default.
• W2375757795 cites W2011319923 @default.
• W2375757795 cites W2016925771 @default.
• W2375757795 cites W2019245377 @default.
• W2375757795 cites W2026461590 @default.
• W2375757795 cites W2027883817 @default.
• W2375757795 cites W2032900060 @default.
• W2375757795 cites W2037163554 @default.
• W2375757795 cites W2038145816 @default.
• W2375757795 cites W2038352373 @default.
• W2375757795 cites W2047272578 @default.
• W2375757795 cites W2054397809 @default.
• W2375757795 cites W2056937171 @default.
• W2375757795 cites W2058750384 @default.
• W2375757795 cites W2059507131 @default.
• W2375757795 cites W2065397525 @default.
• W2375757795 cites W2065748069 @default.
• W2375757795 cites W2068672685 @default.
• W2375757795 cites W2078945917 @default.
• W2375757795 cites W2091345268 @default.
• W2375757795 cites W2104792456 @default.
• W2375757795 cites W2106041086 @default.
• W2375757795 cites W2107431403 @default.
• W2375757795 cites W2111270006 @default.
• W2375757795 cites W2119757776 @default.
• W2375757795 cites W2125610194 @default.
• W2375757795 cites W2130380174 @default.
• W2375757795 cites W2134678910 @default.
• W2375757795 cites W2135940547 @default.
• W2375757795 cites W2141998004 @default.
• W2375757795 cites W2154727263 @default.
• W2375757795 cites W2160977036 @default.
• W2375757795 cites W2168545953 @default.
• W2375757795 cites W4230636610 @default.
• W2375757795 cites W4293247451 @default.
• W2375757795 doi "https://doi.org/10.1016/j.neuroscience.2016.04.048" @default.
• W2375757795 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27181637" @default.
• W2375757795 hasPublicationYear "2016" @default.
• W2375757795 type Work @default.
• W2375757795 sameAs 2375757795 @default.
• W2375757795 citedByCount "32" @default.
• W2375757795 countsByYear W23757577952017 @default.
• W2375757795 countsByYear W23757577952018 @default.
• W2375757795 countsByYear W23757577952019 @default.
• W2375757795 countsByYear W23757577952020 @default.
• W2375757795 countsByYear W23757577952021 @default.
• W2375757795 countsByYear W23757577952022 @default.
• W2375757795 countsByYear W23757577952023 @default.
• W2375757795 crossrefType "journal-article" @default.
• W2375757795 hasAuthorship W2375757795A5056164561 @default.
• W2375757795 hasAuthorship W2375757795A5057333741 @default.
• W2375757795 hasAuthorship W2375757795A5081658503 @default.
• W2375757795 hasConcept C112672928 @default.
• W2375757795 hasConcept C126322002 @default.
• W2375757795 hasConcept C134018914 @default.
• W2375757795 hasConcept C148762608 @default.
• W2375757795 hasConcept C15744967 @default.
• W2375757795 hasConcept C25876315 @default.
• W2375757795 hasConcept C2779234561 @default.
• W2375757795 hasConcept C2781161787 @default.
• W2375757795 hasConcept C44752575 @default.
• W2375757795 hasConcept C54355233 @default.
• W2375757795 hasConcept C71315377 @default.
• W2375757795 hasConcept C71924100 @default.
• W2375757795 hasConcept C86803240 @default.
• W2375757795 hasConceptScore W2375757795C112672928 @default.
• W2375757795 hasConceptScore W2375757795C126322002 @default.
• W2375757795 hasConceptScore W2375757795C134018914 @default.
• W2375757795 hasConceptScore W2375757795C148762608 @default.
• W2375757795 hasConceptScore W2375757795C15744967 @default.
• W2375757795 hasConceptScore W2375757795C25876315 @default.
• W2375757795 hasConceptScore W2375757795C2779234561 @default.

• next