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- W2375769968 abstract "Objective To evaluate the relation between the expression of TIMP 1,TIMP 2 and angiogenesis in colorectal cancer.Methods The expression of TIMP 1,TIMP 2 and the microvessel density(MVD) in paraffin embedded specimens of 52 patients with colorectal cancer were studied by immunohistochemical method.The expressions of TIMP 1 and TIMP 2 were quantitatively analyzed respectively with a computer assisted analysis of digitized microscopic images.Furthermore the relationship between the expression of TIMP 1,TIMP 2 and MVD was analyzed.Results The MVD was significantly higher in positive vessel metastasis group than in the negative group( P 0.05),meanwhile the mean optical density(MOD) of TIMP 2 of cancerous tissue in lower MVD group was significantly higher than that in higher MVD( P 0.05).Conclusion The expression of TIMP 2 of cancerous tissue in colorectal cancer is relative to the inhibition of angiogenesis." @default.
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- W2375769968 date "2000-01-01" @default.
- W2375769968 modified "2023-09-25" @default.
- W2375769968 title "Expression of TIMPs and Angiogenesis in Colorectal Cancer" @default.
- W2375769968 hasPublicationYear "2000" @default.
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