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- W2375804983 abstract "OBJECTIVE To synthesize and characterize N-trimethyl chitosan derivatives having pendant galactose residues for potential gene delivery carriers for hepatocyte-targeting.METHOD Firstly,a water-soluble N-trimethyl chitosan derivatives(TMCS) was prepared.To give galactosylated N-trimethyl chitosan(Gal-TMCS),lactobionic acid was added and galactose group was introduced into the amino groups of TMCS.Lactosaminated N-trimethyl chitosan(Lac-TMCS) was prepared by reaction of TMCS and α-lactose,followed by reaction with KBH_(4).RESULTS FTIR,~(1)H NMR,~(13)C NMR and elemental analysis characterized the chemical structures of N-trimethyl chitosan derivatives having pendant galactose residues.CONCLUSION may be used as potential gene delivery carriers for hepatocyte-targeting." @default.
- W2375804983 created "2016-06-24" @default.
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- W2375804983 date "2005-01-01" @default.
- W2375804983 modified "2023-09-27" @default.
- W2375804983 title "Design,synthesis and characterization of N-trimethyl chitosan derivatives having pendant galactose residues" @default.
- W2375804983 hasPublicationYear "2005" @default.
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