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- W2375814145 abstract "Objective To establish an orthotopic lung transplantation model in the rat, and to evaluate the effects of CZ 1 solution for pulmonary preservation.Methods A total of 18 rats were randomly divided into 3 groups with 5 rats in each group: control group (flushed with equilibrium liquid and transplanted immediately), CZ 1 group (flushed and cold preserved with CZ 1 solution within 8h, then transplanted), and Euro Collins(E C) group (flushed and cold preserved with E C solution, then transplanted). The studied parameters included the ischemia time, PaO 2, PaCO 2, ratio of wet weight to dry weight and the pathological changes of lung grafts. Results For ischemia time, no significant difference between CZ 1 group and E C group was found. For PaO 2, there was a significant difference between control group and CZ 1 group, also between CZ 1 group and E C group. For PaCO 2, there was no significant difference between control group and CZ 1 group, but a significant difference between CZ 1 group and E C group. The ratio of wet weight to dry weight in the control group was apparently higher than in CZ 1 group and E C group, but in E C group it was apparently higher than in CZ 1 group after pure cold preserved. After transplantation and reperfusion, the ratio of wet weight/dry weight in CZ 1 group and E C group was apparently higher than in control group, but in E C group it was higher than in CZ 1 group. The pathological lesions in CZ 1 group was milder than in E C group.Conclusion CZ 1 solution was more effective than E C solution during the 8 h lung preservation." @default.
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- W2375814145 date "1999-01-01" @default.
- W2375814145 modified "2023-09-25" @default.
- W2375814145 title "CZ 1 solution for pulmonary preservation with simplified rat orthotopic lung transplantation using cuff technique" @default.
- W2375814145 hasPublicationYear "1999" @default.
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