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- W2375888904 abstract "Objective To explore the relationship between the left ventricular(LV)wall stress and strain for evaluating the clinical significance of LV systolic function in the patients with hypertension.Methods The left ventricular mass index (LVMI), relative wall thickness (RWT), ejection fraction (EF) and cardiac index (CI) were evaluated by echocardiography in 55 cases with essential hypertension and 30 normal control subjects. LV wall meridional peak systolic stress (Pσm) was calculated by brachial blood pressure. Patients with hypertension were divided into patterns of normal geometric LV and remodeling LV according to LVMI and RWT. Quantitative tissue velocity imaging (QTVI) was applied for obtaining the basal and middle segments of LV anterior wall long axis strain curve and peak systolic strain. Results ①The LV systolic function was decreased (EF and CI) in hypertension with remodeling LV group (P0.01), but no significant change in hypertension with normal geomertric LV group. ②Pσm was higher in two hypertension groups than in the control group (P0.05-0.01), and it had significant difference between two hypertension groups (P0.01). ③The PSS of the basal and middle segments in LV anterior wall was lower in two hypertension groups than in the control group (P0.01), and it had significant difference between two hypertension groups (P0.01). ④There is remarkably negative correlation between Pσm and PSS(Bas and Mid). To calculate the Pσm and PSSBas in the normal geometric group according to the regression equation at the same stress level, the result was that the real measured value of the PSSBas significantly lower than the estimated value of the PSSBas and the ratio of the real measured value and the estimated value of the PSSBas in remodeling geometric group decreased significantly than in normal geometric group (P0.01). Conclusion ①The relationship of LV wall stress and strain was independent on the after load of the heart. ②To evaluate the myocardial contractility by applying the relationship of LV wall stress and strain is able to reflect biomechanical character of myocardium more objectively, and it may be a useful method in evaluating the pathophysiological changes of myocardium in vivo." @default.
- W2375888904 created "2016-06-24" @default.
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- W2375888904 date "2003-01-01" @default.
- W2375888904 modified "2023-09-24" @default.
- W2375888904 title "Relationship between Left Ventricular Wall Stress and Strain:Evaluating Left Vertrical Systolic Function in the Patients with Hypertension" @default.
- W2375888904 hasPublicationYear "2003" @default.
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