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- W2375923502 abstract "Objective:To study the relationship between chromosome abnormity and their phenotype, and analyze the detection rate of abnormal chromosome, abnormal phenotype and frequency distribution.Methods:Among 1624 patients consulted in infertility clinic in our hospital from recent 6 years, chromosome karyotype and clinical analysis were conducted in abnormal chromosome patients.Results:Out of 1624 infertility patients, 184 cases were with chromosome abnormity. The numbers of euchromosome abnormalities were 79 (42.93%). The number of sex chromosome abnormalities and abnormal sex chromosome structure were 31 and 74, respectively, and they accounted for 16.85% and 40.22%, respectively. Among 184 cases with abnormal chromosome, 21 cases were azoospermia (11.41%) and 23 cases were oligospermia (12.50%). 96 cases were recurrent spontaneous abortion and multiple fetal death during pregnancy (52.17%). Delivery of terata was 23 (12.50%), mental retardation and abnormal development were 21 (11.41%).Conclusions:Chromosome abnormity is one of the important factors in patients with infertility. Chromosome examination should be performed to exclude the possibility of chromosome abnormity in patients with obstinate infertility." @default.
- W2375923502 created "2016-06-24" @default.
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- W2375923502 date "2011-01-01" @default.
- W2375923502 modified "2023-09-23" @default.
- W2375923502 title "Clinical Analysis of 184 Cases with Chromosomal Abnormality in 1624 Infertility Patients" @default.
- W2375923502 hasPublicationYear "2011" @default.
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