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- W2375953881 abstract "The objective of this research was to study the radiosensitization effect of RHuEpo on middle-advanced esophageal cancer,from March 2004 to May 2005,64 patients with middle-advanced esophageal cancer were randomly divided into two groups:the trial group and control group.In the trial group,RHuEpo was administered at 30 000 U weekly during the course of radiation and one week before radiation.The control group was given single radiation.Radiation was administered with 6 MV X-rays,1.8-2.0 Gy per day and 5 times per week.The total dose was 60-70 Gy over 6-7 weeks,and the median doses were 64 Gy and 65 Gy,respectively.At the end of DT 20 Gy,complete remission rates(CRR)in the both groups were 6.5%(2/31),χ2=0.267 2,P=0.605 2,while DT 40 Gy was over,CRR(s)were 32.3%(10/31)and 16.1%(5/31),χ2=2.198 6,P=0.138 1,respectively,when the whole radiotherapy was finished,CRR(s)were 48.4%(15/31)and 25.8%(8/31),χ2=3.386 8,P=0.065 7,respectively,and one month and six months after the radiotherapy,CRR(s)were 61.3%(19/31)and 64.5%(20/31)in the trial group,and 35.5%(11/31)and 38.7%(12/31)in the control group,respectively(χ2=4.133 3,P=0.042 0;χ2=4.133 3,P=0.042 0).The rates of acute hematological toxicity were different the in two groups,χ2=5.247 6,P=0.022 0.In conclusion,RHuEpo can improve the clinical effect of patients with middle-advanced esophageal cancer who received radiotherapy,deerease acute hematological toxicity caused by radiotherapy,and may elongate life time of these patients." @default.
- W2375953881 created "2016-06-24" @default.
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- W2375953881 date "2007-01-01" @default.
- W2375953881 modified "2023-09-23" @default.
- W2375953881 title "Study of radiosensitization effect of RHuEpo on middle-advanced esophageal cancer" @default.
- W2375953881 hasPublicationYear "2007" @default.
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