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- W2375974840 abstract "Objective To assess the efficacy of aripiprazole on the treatment of senile schizophrenia.Methods A randomized,doubl-blind,double-dummy,comparative study was performed with a cours of 6 weeks.Fifty-six patients with schizophrenia were randomized into aripiprazole group(n=28) and risperidone group(n=28).The positive and negative syndrome scale,clinical global impression,treatment emergent symptom scale were used to assess the effectiveness and the safety of the treatment.Results By the end of the 6 week treatment,in both groups,the scores of PANSS decreased significantly comparing to the baseline(P 0.05) without statistically different between two groups.By the end of 6 week,total clinical effective rates were 61.5% in aripiprazole group and 72% in brisperidone group,without any statistically significant difference beween the two groups(x 2 =0.16,P 0.05).No severe adverse events were reported in both groups,However,the tremor and akathisia in aripiprazole group was much lower than in risperidone group.Conclusion Both aripiprazole and risperidone are effective in the treatment of senile schizophrenia,but aripiprazole has better safety and compliance and is more suitable for senile schizophrenia." @default.
- W2375974840 created "2016-06-24" @default.
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- W2375974840 date "2012-01-01" @default.
- W2375974840 modified "2023-09-23" @default.
- W2375974840 title "A control study of aripiprazole and risperidone on the treatment of senile schizophrenia" @default.
- W2375974840 hasPublicationYear "2012" @default.
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