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- W2376009908 abstract "OBJECTIVE To investigate the distribution of 36 kinds of acquired resistance genes and 3 kinds of genetic markers of integrons in Klebsiella pneumoniae isolates.METHODS From Aug 2005 to Feb 2006,20 strains of K.pneumoniae isolated from sputum were collected from a city level hospital in Jiangsu.then,21kinds of acquired β-lactam-resistance genes,15 kinds of acquired aminoglycoside-resistance genes as well as 3 kinds of genetic markers of integrons were analyzed by PCR.And hierarchical cluster analysis was used to investigate the correlation between acquired resistance genes and genetic markers of integrons.RESULTS In 20 strains of K.pneumoniae,7 kinds of acquired β-lactam-resistance genes,5 kinds of acquired aminoglycoside-resistance genes and 1 kind of integron.But other 26 kinds of genes could not be detected.CONCLUSIONS Detected rate of acquired β-lactam-resistance genes is higher than that of acquired aminoglycoside-resistance genes,which is identical to phenotype.And hierarchical cluster analysis shows that correlation might exist between 8 kinds of genes and intⅠ1,which suggests that these genes might locate on class Ⅰintegron." @default.
- W2376009908 created "2016-06-24" @default.
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- W2376009908 date "2011-01-01" @default.
- W2376009908 modified "2023-09-23" @default.
- W2376009908 title "Detection of acquired resistance genes in Klebsiella pneumoniae isolates and cluster analysis of indicators" @default.
- W2376009908 hasPublicationYear "2011" @default.
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