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- W2376044128 abstract "Objective To discuss the association of apolipoprotein E-gene polymorphism with Alzheimer's disease(AD) and multi-infarct dementia(MID).Methods The polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP) technique was used to analyze the apoE genotypes of 102 dementia patients and 76 control subjects.Results The frequency of apoE e4 increased significantly,but the frequency of e3 decreased significantly in AD.The result was quite different from that of the control subjects(P0.01).There was no significant difference of the frequency of apoE allele gene between MID and the control subjects.Conclusion The study indicates that apoE e4 allel gene is a risk factor in AD.The association of apoE e4 allele gene with MID needs to be studied continuously." @default.
- W2376044128 created "2016-06-24" @default.
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- W2376044128 date "2009-01-01" @default.
- W2376044128 modified "2023-09-24" @default.
- W2376044128 title "Study on the Association of Apolipoprotein E-gene Polymorphism with Demented Patients" @default.
- W2376044128 hasPublicationYear "2009" @default.
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