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• W2376062008 abstract "Objective To discuss the value of soluble triggering receptor expressed on myeloid cells-1(sTREM-1) in exhaled ventilator condensate(EVC) in the early diagnose of patients with ventilator-associated pneumonia(VAP).Methods sTREM-1 in EVC was determined in 37 adult patients with mechanical ventilation treatment by double antibody sandwich enzyme-linked immunosorbant assay(DAS-ELISA).The 37 patients were divided into the non-VAP group with 13 cases and the VAP group with 24 cases,and the VAP group included the recovery subgroup(14 cases) and the aggravation subgroup(10 cases).The levels of sTREM-1 in EVC was measured on Day 1,3 and 7 for all patients.The early diagnostic value was assessed by receiver operating characteristic(ROC) curve analysis.Results On the 3th day,the levels of EVC,sTREM-1 and serum CRP were obviously higher in the VAP group than in the non-VAP group(P 0.01).On the 7th day,the levels of EVC,sTREM-1 and serum CRP were still higher in the aggravation subgroup than in the recovery subgroup and the non-VAP group(P 0.01),but there was no significant difference between the non-VAP group and the recovery subgroup(P 0.05).The dividing value of sTREM-1 in the early diagnosis of patients with VAP was 4.70 ng / ml on the 3rd day by ROC curve analysis.The sensitivity was 85.8%,and the specificity was 92.3%.Conclusion The results suggest that the levels of sTREM1 in EVC is conducive to the early diagnosis of VAP,and the levels of sTREM-1 in EVC and serum CRP are helpful to estimate the prognosis on the 7th day,including ventilator weaning failure and death." @default.
• W2376062008 created "2016-06-24" @default.
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• W2376062008 date "2013-01-01" @default.
• W2376062008 modified "2023-09-23" @default.
• W2376062008 title "Clinical value of soluble triggering receptor expressed on myeloid cells-1 in the early diagnosis of patients with ventilator-associated pneumonia" @default.
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